Naloxone 400mcg/1ml Ampoule POM x10

Solution for injection/infusion - Clear and colourless solution

Each ampoule of 1 ml contains 0.4 mg naloxone hydrochloride (as naloxone hydrochloride dihydrate).

Therapeutic indications
• Complete or partial reversal of CNS and especially respiratory depression, caused by natural or synthetic opioids.
• Diagnosis of suspected acute opioid overdose or intoxication.
• Complete or partial reversal of respiratory and other CNS depression in the neonate whose mothers have received opioids.

Features

Nature and contents of container
• Type I clear, colourless glass ampoules.
• Packs of 5 or 10 ampoules of 1 ml.

Special precautions for storage
• Keep the ampoules in the outer carton in order to protect from light.
• Store below 25°C.
• Store diluted solutions below 25°C.

Shelf life
• 3 years.
Shelf-life after first opening
• After first opening the medicinal product should be used immediately.
Shelf-life after dilution
•Chemical and physical in-use stability has been demonstrated for 24 hours below 25°C.

From the microbiological point of view, the dilutions should be used immediately. If not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2 to 8 °C, unless dilution has taken place in controlled and validated aseptic conditions.